ai.nullary/nullary

up checked 2026-11-11T04:38:21.231Z

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Publisher-provided description

Negative results intelligence for drug discovery — query measured failures via MCP.

Summary by lookupd

Lets agents query measured negative results in drug discovery, including failed compounds, ADMET, safety, and clinical history across…

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http nullary https://mcp.nullary.ai/mcp

Codex, remote (streamable-http)

codex mcp add nullary --url https://mcp.nullary.ai/mcp

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "nullary": {
      "url": "https://mcp.nullary.ai/mcp"
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Tools (showing 30 of 35)

Publisher-provided text

• search_inactive_compounds Inactive small-molecule compound-target pairs.
• search_failed_selectivity Small molecules that failed selectivity.
• search_admet_failures Small-molecule ADMET failures.
• search_failed_guides Failed/ineffective CRISPR guides.
• search_failed_essentiality_screens Non-dependency / failed essentiality screens.
• search_ancestry_specific_failures Ancestry-specific CRISPR failures.
• search_developability_failures Antibody developability failures.
• search_failed_clinical_antibodies Discontinued/terminated clinical antibodies.
• search_failed_peptide_therapeutics Failed peptide therapeutics.
• search_peptide_stability_issues Peptide stability/half-life failures.
• search_failed_protacs PROTACs that failed degradation/ternary/permeability.
• search_protac_e3_issues PROTAC E3-ligase recruitment / ternary failures.
• search_failed_oligonucleotides ASOs/siRNAs that failed engagement/developability.
• search_oligo_delivery_failures Oligonucleotide delivery failures.
• search_failed_vaccines Failed/terminated vaccines (by pathogen/indication).
• search_vaccine_immunogenicity_failures Failed vaccine immunogen designs.
• search_failed_adcs ADCs that failed at any stage.
• search_adc_linker_failures ADC failures attributed to linker chemistry.
• search_failed_bispecifics Bispecifics that failed at any stage.
• search_bispecific_format_failures Bispecific format/engineering failures.
• search_admet_failures_all_modalities ADMET failures across ALL modalities.
• search_drug_drug_interaction_failures Drug-drug interaction failures.
• search_mechanism_failures Approaches that failed for a mechanism (by target).
• search_failed_replications Findings that failed to replicate.
• search_safety_failures Clinical/preclinical safety failures across modalities.
• search_target_history ALL failed approaches against a target across every modality.
• search_indication_history ALL failed approaches for an indication across every modality.
• search_pathogen_history Vaccine + antimicrobial + antibody failures for a pathogen.
• get_compound A compound (structure, name, max clinical phase) + its full negative profile across modalities/sources.
• get_finding_provenance Full provenance + detail for a single finding by id.

Details

• Version: 1.0.1
• Transports: streamable-http
• Uptime (7 days): 100%
• Median latency: 441 ms
• First indexed: 2026-11-01T08:50:38.658Z
• Last seen in registry: 2026-11-01T08:50:38.668Z
• Repository: https://github.com/nullary-ai/nullary

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[![lookupd status](https://lookupd.com/badge/ai.nullary/nullary.svg)](https://lookupd.com/servers/ai.nullary/nullary)

• 62033 servers
• Last crawl: 2026-11-11T15:38:39.561Z
• API base: https://api.lookupd.com
• MCP URL: https://api.lookupd.com/mcp