app.ivive/ivive

up checked 2026-11-11T06:39:57.713Z

Unclaimed · Unverified

Publisher-provided title

ivive.app

Publisher-provided description

Human hepatic clearance from in-vitro CLint, with the error band measured on known drugs.

Summary by lookupd

Predicts human hepatic and plasma clearance from in-vitro data and scales animal clearance to humans, with measured error bands and…

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http ivive https://api.ivive.app/mcp/

Codex, remote (streamable-http)

codex mcp add ivive --url https://api.ivive.app/mcp/

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "ivive": {
      "url": "https://api.ivive.app/mcp/"
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Publisher-provided text

predict_inputs Predict fu,p and fu,inc from a SMILES, with structure-only human CL and Vss as second opinions. Predictions, not measurements; check the applicability verdict.
calc_clhep Hepatic and plasma clearance from in-vitro CLint, fu,mic and fu,p (IVIVE), with the observed-CL band and applicability warnings. If fu,p or fu,mic came from pre
target_clint The in-vitro CLint an assay must read for a compound to reach a target plasma clearance (mL/min/kg): calc_clhep run backwards, e.g. to set a CLint cut-off for a
input_sensitivity How far plasma CL moves as each input is varied over a range, e.g. a predicted fu,p over its 50% range.
similar_drugs Nearest reference drugs to a SMILES (Tanimoto, Morgan radius 2), each with measured human plasma CL and the CL IVIVE predicted from its measured inputs. Use it
scale_to_human Predict human plasma CL from observed animal in-vivo CL (rat, dog, monkey), every applicable method with its measured error. Observed animal CL only, never pred

Shows this live status and links here; updates hourly.

[![lookupd status](https://lookupd.com/badge/app.ivive/ivive.svg)](https://lookupd.com/servers/app.ivive/ivive)