io.github.cyanheads/interpro-mcp-server

up checked 2026-11-10T23:38:02.679Z

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Publisher-provided description

Search InterPro entries, map domains onto proteins and PDB structures, and scan raw sequences.

Summary by lookupd

Searches InterPro entries, maps protein domains and PDB chain matches, and submits raw sequences for domain scanning.

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http interpro-mcp-server https://interpro.caseyjhand.com/mcp

Claude Code, npm package (stdio)

claude mcp add interpro-mcp-server -- npx -y @cyanheads/interpro-mcp-server

Claude Code, npm package (stdio)

claude mcp add interpro-mcp-server -- npx -y @cyanheads/interpro-mcp-server

Codex, remote (streamable-http)

codex mcp add interpro-mcp-server --url https://interpro.caseyjhand.com/mcp

Codex, npm package (stdio)

codex mcp add interpro-mcp-server -- npx -y @cyanheads/interpro-mcp-server

Codex, npm package (stdio)

codex mcp add interpro-mcp-server -- npx -y @cyanheads/interpro-mcp-server

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "interpro-mcp-server": {
      "url": "https://interpro.caseyjhand.com/mcp"
    }
  }
}

Cursor, npm package (stdio) → .cursor/mcp.json

{
  "mcpServers": {
    "interpro-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/interpro-mcp-server"
      ]
    }
  }
}

Cursor, npm package (stdio) → .cursor/mcp.json

{
  "mcpServers": {
    "interpro-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/interpro-mcp-server"
      ]
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Tools (9 tools)

Publisher-provided text

• interpro_list_reference List supported InterPro database slugs, entry types, accession and PDB identifier patterns, common taxon IDs, or current release information.
• interpro_search_entries Search InterPro entries or member signatures by text or entry type. GO filters require sourceDatabase interpro; integratedInto selects member signatures for an
• interpro_get_entry Retrieve one InterPro or member-database entry with full metadata by default. Select optional sections while retaining core and unknown metadata, or supply over
• interpro_get_clan Retrieve a Pfam, CDD, or PIRSF clan/set and a cursor page of member entries; optionally include its relationship graph, returned in slices that fit the response
• interpro_get_protein_domains Retrieve InterPro and member-signature matches on a canonical UniProt protein, preserving every location and discontinuous fragment. Optionally select records c
• interpro_find_proteins_by_domain Find UniProt proteins carrying an InterPro or member signature. Defaults to reviewed human proteins; reviewedOnly=false includes all review statuses in the chos
• interpro_get_structure_domains Retrieve InterPro and member-signature matches on one PDB entry's protein chains. Each chain record keeps match locations in chain numbering (1-based start/end
• interpro_scan_sequence Find InterPro domain, family, and site matches for one raw protein sequence that has no UniProt accession. Sequences already in UniParc return precalculated mat
• interpro_get_scan_result Check an InterProScan job started by interpro_scan_sequence, waiting up to waitSeconds for it to finish. Returns the matches once finished, otherwise its queued

Details

• Version: 0.2.0
• Transports: streamable-http, stdio
• Uptime (7 days): 100%
• Median latency: 986 ms
• First indexed: 2026-11-01T09:26:07.840Z
• Last seen in registry: 2026-11-01T09:26:07.869Z
• Repository: https://github.com/cyanheads/interpro-mcp-server

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