io.github.cyanheads/uniprot-mcp-server

up checked 2026-11-11T01:38:21.712Z

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Publisher-provided description

Protein research over UniProtKB: search by function, fetch curated records, map IDs, proteomes.

Summary by lookupd

Search UniProtKB, fetch curated protein records and sequences, map identifiers across databases, and look up proteomes and taxonomy.

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http uniprot-mcp-server https://uniprot.caseyjhand.com/mcp

Claude Code, npm package (stdio)

claude mcp add uniprot-mcp-server -- npx -y @cyanheads/uniprot-mcp-server

Claude Code, npm package (stdio)

claude mcp add uniprot-mcp-server -- npx -y @cyanheads/uniprot-mcp-server

Codex, remote (streamable-http)

codex mcp add uniprot-mcp-server --url https://uniprot.caseyjhand.com/mcp

Codex, npm package (stdio)

codex mcp add uniprot-mcp-server -- npx -y @cyanheads/uniprot-mcp-server

Codex, npm package (stdio)

codex mcp add uniprot-mcp-server -- npx -y @cyanheads/uniprot-mcp-server

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "uniprot-mcp-server": {
      "url": "https://uniprot.caseyjhand.com/mcp"
    }
  }
}

Cursor, npm package (stdio) → .cursor/mcp.json

{
  "mcpServers": {
    "uniprot-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/uniprot-mcp-server"
      ]
    }
  }
}

Cursor, npm package (stdio) → .cursor/mcp.json

{
  "mcpServers": {
    "uniprot-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/uniprot-mcp-server"
      ]
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Tools (6 tools)

Publisher-provided text

• uniprot_search_proteins Search UniProtKB and return curated protein records. Pass text_search for a plain-language query (the 80% case) or query for the full Lucene field syntax (gene:
• uniprot_get_entry Fetch full curated UniProtKB entries by accession in one batch (up to 20). Each entry carries function, catalytic activity, cofactors, subcellular location, dis
• uniprot_map_ids Translate identifiers across databases via UniProt's ID-mapping service — gene names to accessions, accession to PDB / Ensembl / RefSeq / ChEMBL / GeneID, and b
• uniprot_get_proteome Fetch the reference proteome for an organism by UPID (e.g. "UP000005640") or NCBI taxon ID (e.g. 9606) — provide exactly one. Returns metadata inline: proteome
• uniprot_get_taxonomy Resolve a taxonomy record by NCBI taxon ID (e.g. 9606) or organism name (e.g. "Homo sapiens" or "human") — provide exactly one. Exact case-insensitive scientifi
• uniprot_get_sequence Fetch the canonical amino-acid sequence (FASTA) for a UniProtKB accession, with length and the parsed header. Set include_isoforms to also return the alternativ

Details

• Version: 0.4.0
• Transports: streamable-http, stdio
• Uptime (7 days): 100%
• Median latency: 690 ms
• First indexed: 2026-11-01T09:26:43.915Z
• Last seen in registry: 2026-11-04T03:17:15.164Z
• Repository: https://github.com/cyanheads/uniprot-mcp-server

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