io.github.sanjaysgk/can-immune

up checked 2026-11-11T15:37:55.970Z

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Publisher-provided description

Query CAN-IMMUNE: cancer neoantigen mutations, peptides, cell lines, MHC-I binding. Read-only.

Summary by lookupd

Queries cancer neoantigen mutation data, including genes, cell lines, peptides and cached MHC-I binding predictions, in read-only mode.

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http can-immune https://canelib.erc.monash.edu/mcp

Codex, remote (streamable-http)

codex mcp add can-immune --url https://canelib.erc.monash.edu/mcp

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "can-immune": {
      "url": "https://canelib.erc.monash.edu/mcp"
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Tools (12 tools)

Publisher-provided text

• database_overview Get the headline size of the CAN-IMMUNE database in one call. Returns total counts of mutations, genes, and unique mutant peptides, plus how many cell
• search_genes Find genes by symbol or full name, ranked by how mutated they are. Matches the gene symbol OR the full gene name (partial, case-insensitive) and return
• get_gene Get the full profile for one gene by exact symbol. Returns total mutations and how they split between cell lines vs tissues, unique mutant peptides, sa
• search_cell_lines Find cancer cell lines by name, ranked by mutation burden. Returns each matching cell line with its tissue of origin, cancer type, total mutations, uni
• get_cell_line Get the full profile for one cancer cell line by exact name. Returns tissue of origin, cancer type, total mutations, unique mutant peptides and genes,
• top_genes_in_cell_line Rank the most-mutated genes within one specific cell line. Answers "what is the top mutated gene in <cell line>" / "which genes are most altered in <ce
• list_cancer_types List cancer types (histology) ranked by mutation burden. Returns each cancer type / histology with its total mutations, unique samples, and unique gene
• list_tissues List primary tissues ranked by mutation burden. Returns each tissue (COSMIC primary-tissue samples only, kept separate from cell lines) with its total
• get_gene_mutations List individual mutations in a gene (a bounded sample of rows). Each row gives the CAN-IMMUNE mutation ID (CANLIB...), the amino-acid change, the CDS c
• get_mhc_binding Look up a CACHED MHC-I binding prediction for a peptide + HLA allele. Returns the NetMHCpan result (best binding core, %Rank_EL, binder level SB/WB/NB,
• search Search CAN-IMMUNE for genes and cell lines (ChatGPT connector interface). Returns {results: [{id, title, url}]} combining matching genes and cell lines,
• fetch Fetch the full record for an id returned by `search` (ChatGPT connector interface). Takes an id like 'gene:TP53' or 'cell_line:MDA-MB-231' and returns

Details

• Version: 1.0.0
• Transports: streamable-http
• Uptime (7 days): 100%
• Median latency: 1303 ms
• First indexed: 2026-11-01T09:53:44.370Z
• Last seen in registry: 2026-11-01T09:53:44.370Z
• Repository: https://github.com/sanjaysgk/can-immune-mcp
• Website: https://canelib.erc.monash.edu/connector

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