net.genebe/genebe-mcp

up checked 2026-11-11T03:38:07.106Z

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Publisher-provided title

GeneBe

Publisher-provided description

Annotate and classify human genetic variants with GeneBe (ACMG, gnomAD, ClinVar). Research use only.

Summary by lookupd

Annotates and classifies human genetic variants, converts coordinates between genome builds, and looks up gene and transcript data for…

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http genebe https://mcp.genebe.net/v1/mcp

Codex, remote (streamable-http)

codex mcp add genebe --url https://mcp.genebe.net/v1/mcp

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "genebe": {
      "url": "https://mcp.genebe.net/v1/mcp"
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Publisher-provided text

annotate_variant Annotate and classify one human genetic variant using GeneBe. Start here for any question about a variant (what is it, is it pathogenic/benign, how common is i
explain_acmg_decision_path Explain step by step why each classification criterion did or did not apply to a variant. Use after annotate_variant when the user asks "why was this classifie
convert_variant Convert a variant written in any notation into normalized hg38 genomic coordinates. Use when you only need the chr/pos/ref/alt of a variant (for example to tra
get_variant_effects List a variant's predicted molecular consequences on every overlapping transcript. Returns per-transcript HGVS (c. and p.), consequence terms (e.g. missense_va
get_gene Look up a human gene: identifiers, location, MANE Select transcript, ClinGen gene-disease validity. Use for questions about a gene rather than a specific varia
liftover_coordinate Convert a genomic position, interval or variant between genome builds (hg19, hg38, t2t). Check `status`: RESOLVED means one result, AMBIGUOUS means several can

Shows this live status and links here; updates hourly.

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