world.sniff/sniff-mcp

up checked 2026-11-11T11:38:31.913Z

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Publisher-provided description

Canine genomics for agents: breed allele frequencies, AI pathogenicity + OMIA clinical disease layer

Summary by lookupd

Query a canine genomics atlas for breed allele frequencies, variant annotations, breed similarity, and OMIA inherited disease records.

Install

Claude Code, remote (streamable-http)

claude mcp add --transport http sniff https://mcp.sniff.world/mcp/

Codex, remote (streamable-http)

codex mcp add sniff --url https://mcp.sniff.world/mcp/

Cursor, remote (streamable-http) → .cursor/mcp.json

{
  "mcpServers": {
    "sniff": {
      "url": "https://mcp.sniff.world/mcp/"
    }
  }
}

Other clients: docs. Or tell your agent: Set up lookupd for me: read https://lookupd.com/agent.md and follow it.

Tools (18 tools)

Publisher-provided text

• ask Ask Sniff a natural-language canine-genetics question and get a GROUNDED, CITED answer (or an honest abstain). Covers inherited diseases (OMIA) and their human
• ask_the_graph THE INSTRUMENT — ask a free-form CROSS-SPECIES genetics question and get FILTERED, HONEST HINTS (never a confident guess). It compiles your question into a type
• disease_bridge The fused OMIA disease layer as cited atoms. Give a `disease` (name or 'OMIA:001870-9615') for its genes, inheritance, human homolog (OMIM/Mondo bridge), and va
• ask_variant_context THE headline query. Given a CanFam4 position (e.g. '5:56189113'), return the variant's global + popmax frequency, breed-stratified cross-breed frequencies, Pang
• variant_lookup Single-variant lookup by CanFam4 position: ref/alt, global + popmax AF, consequence, gene, Pangolin and phyloP annotations, canonical URL, provenance.
• breed_variant_frequency Breed-stratified allele frequency. Give a breed (e.g. 'bernese_mountain_dog') plus either a variant position or a gene symbol. Returns AF (+ rank) for the varia
• gene_summary Variants in a gene (by gene symbol), ranked by impact then allele frequency. Paginated (limit, default 25); returns total_variants. Use af_min to filter by glob
• breed_summary Breed profile: n_dogs, breed group, genetic geometry and nearest breeds. Descriptive only — not a health ranking.
• variant_search Filtered discovery over all 9.67M variants. Predicates (combine freely): phylop_min (phyloP >=), popmax_min (popmax AF >=), gene_in (list of gene symbols), cons
• nearest_breeds Genetically nearest breeds to the given breed (top-10-PC Euclidean in canine genetic space). Answers 'what breeds are most genetically similar to X?' via the PC
• breed_similarity Genetic distance between two breeds (top-10-PC Euclidean). Lower = more genetically similar.
• semantic_search Faceted hybrid + semantic-ranker search over the whole knowledge base (diseases, breeds, Scout discoveries). Use for fuzzy/thematic intent ('drug sensitivity in
• disease_links A canine inherited disease (name or OMIA id) -> its governed OMIA clinical record: mode of inheritance, causal gene(s), curated description (summary / clinical
• disease_lookup Look up a canine inherited disease by name or OMIA id -> its governed OMIA clinical record (inheritance, causal gene(s), curated description, clinical signs, hu
• search_diseases Search the canine disease catalogue by free text -> ranked candidates [{omia_id, disease, url, score}]. Use before disease_lookup when the exact name is unknown
• breeds_in_atlas List all 188 breeds with breed-stratified frequencies in the atlas.
• genes_indexed Top genes by number of variants in the atlas (discovery aid).
• metadata Atlas metadata: release, DOI, assembly, variant/breed counts, scope banner, and the RPC catalog.

Details

• Version: 1.1.0
• Transports: streamable-http
• Uptime (7 days): 100%
• Median latency: 1406 ms
• First indexed: 2026-11-01T10:09:39.792Z
• Last seen in registry: 2026-11-01T10:09:39.804Z
• Repository: https://github.com/Sniffscore/sniff-mcp
• Website: https://sniff.world

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